Cinzia Perrino Selected Research

beta Adrenergic Receptors

3/2010	[Novel concepts in beta-adrenergic receptor signaling: therapeutic options for heart failure].
11/2007	Dynamic regulation of phosphoinositide 3-kinase-gamma activity and beta-adrenergic receptor trafficking in end-stage human heart failure.
8/2006	Targeted inhibition of phosphoinositide 3-kinase activity as a novel strategy to normalize beta-adrenergic receptor function in heart failure.
6/2006	Intermittent pressure overload triggers hypertrophy-independent cardiac dysfunction and vascular rarefaction.
6/2005	Targeted inhibition of beta-adrenergic receptor kinase-1-associated phosphoinositide-3 kinase activity preserves beta-adrenergic receptor signaling and prolongs survival in heart failure induced by calsequestrin overexpression.
5/2005	Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/phosphoinositide 3-kinase complex.
8/2004	Network integration of the adrenergic system in cardiac hypertrophy.
7/2003	Role of phosphoinositide 3-kinase in cardiac function and heart failure.

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Cinzia Perrino Research Topics

Disease

15	Heart Failure 01/2019 - 07/2003
6	Infarction (Infarctions) 01/2021 - 10/2006
5	Aortic Valve Stenosis (Aortic Stenosis) 01/2020 - 09/2014
5	Cardiomegaly (Heart Hypertrophy) 06/2011 - 10/2002
4	Myocardial Infarction 01/2021 - 05/2013
4	Mitochondrial Diseases (Mitochondrial Disease) 01/2018 - 10/2010
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 01/2018
3	Heart Diseases (Heart Disease) 01/2022 - 01/2016
3	Inflammation (Inflammations) 01/2019 - 02/2011
3	Fibrosis (Cirrhosis) 04/2018 - 06/2011
3	Hypoxia (Hypoxemia) 01/2018 - 05/2013
2	Acute Coronary Syndrome 09/2020 - 01/2018
2	Hypertrophy 01/2018 - 07/2003
2	Reperfusion Injury 06/2017 - 05/2017
2	ST Elevation Myocardial Infarction 05/2017 - 01/2017
2	Atrial Fibrillation 10/2016 - 01/2016
2	Chronic Renal Insufficiency 02/2015 - 01/2015
2	Mitral Valve Insufficiency (Mitral Regurgitation) 01/2015 - 09/2014
2	Neoplasms (Cancer) 01/2014 - 06/2012
2	Aneurysm (Aneurysms) 01/2013 - 11/2009
2	Ischemia 06/2010 - 06/2004
1	COVID-19 01/2021
1	Infections 01/2021
1	Diabetes Mellitus 01/2018
1	Hyperglycemia 01/2018
1	Fibrosarcoma 01/2017
1	Myocardial Ischemia (Ischemic Heart Diseases) 01/2016
1	Acute Kidney Injury (Acute Renal Failure) 09/2015
1	Mucopolysaccharidoses 01/2015
1	Mucopolysaccharidosis III (Sanfilippo Syndrome) 01/2015
1	Heart Valve Diseases (Valvular Heart Disease) 01/2015
1	Endoleak 01/2013
1	Aortic Aneurysm (Aneurysm, Aortic) 01/2013
1	Alzheimer Disease (Alzheimer's Disease) 06/2012
1	Dilated Cardiomyopathy (Cardiomyopathy, Congestive) 09/2011
1	Thrombosis (Thrombus) 06/2010
1	Body Weight (Weight, Body) 01/2010
1	Hypertension (High Blood Pressure) 01/2010

Drug/Important Bio-Agent (IBA)

8	beta Adrenergic ReceptorsIBA 03/2010 - 07/2003
6	Phosphotransferases (Kinase)IBA 06/2011 - 06/2004
5	Phosphatidylinositols (Phosphatidylinositol)IBA 02/2011 - 07/2003
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 01/2010
3	Peptides (Polypeptides)IBA 09/2015 - 10/2010
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 05/2013
2	Oxidoreductases (Dehydrogenase)IBA 01/2018 - 10/2002
2	Proteins (Proteins, Gene)FDA Link 01/2018 - 01/2017
2	EnzymesIBA 01/2015 - 09/2011
2	DNA Nucleotidylexotransferase (Terminal Deoxynucleotidyl Transferase)IBA 05/2013 - 05/2006
1	CytokinesIBA 01/2021
1	trans-crotonin (CTN)IBA 01/2021
1	omega-Chloroacetophenone (Mace)IBA 01/2021
1	TroponinIBA 01/2021
1	GoldIBA 01/2020
1	GTP Phosphohydrolases (GTPases)IBA 01/2018
1	NSC 23766IBA 01/2018
1	Carvedilol (Coreg)FDA LinkGeneric 01/2018
1	Adenosine Monophosphate (AMP)IBA 01/2018
1	Metoprolol (Toprol-XL)FDA LinkGeneric 01/2018
1	NADP (NADPH)IBA 01/2018
1	MelatoninIBA 01/2017
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 01/2016
1	dermcidinIBA 09/2015
1	dicarboxydine (DCD)IBA 09/2015
1	Small Interfering RNA (siRNA)IBA 09/2015
1	MyokinesIBA 09/2015
1	salicylhydroxamic acid (SHAM)IBA 09/2015
1	Natriuretic PeptidesIBA 01/2015
1	Protein Isoforms (Isoforms)IBA 01/2015
1	Myosins (Myosin)IBA 01/2015
1	Heparitin Sulfate (Heparan Sulfate)IBA 01/2015
1	Acetylglucosaminidase (NAGase)IBA 01/2015
1	Beclin-1IBA 01/2015
1	CollagenIBA 01/2015
1	Connexin 43 (Connexin43)IBA 01/2015
1	Calcium-Calmodulin-Dependent Protein KinasesIBA 01/2015
1	alpha-N-acetyl-D-glucosaminidase (alpha-N-acetylglucosaminidase)IBA 01/2015
1	ActininIBA 01/2015
1	Pharmaceutical PreparationsIBA 01/2014
1	Uncoupling Protein 3IBA 05/2013
1	Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA 06/2012
1	Tissue Inhibitor of MetalloproteinasesIBA 09/2011
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 09/2011
1	Intercellular Signaling Peptides and Proteins (Growth Factors)IBA 09/2011
1	Pen(5)-Trp(7)-Orn(8)- urotensin II (4-11)IBA 06/2011
1	urotensin IIIBA 06/2011
1	ArrestinIBA 06/2011
1	Polytetrafluoroethylene (Teflon)FDA Link 06/2010
1	nitinolIBA 06/2010
1	Extracellular Signal-Regulated MAP Kinases (Extracellular Signal Regulated Kinases)IBA 01/2010
1	Messenger RNA (mRNA)IBA 01/2010
1	Atrial Natriuretic Factor (ANF)IBA 01/2010

Therapy/Procedure

14	Therapeutics 01/2022 - 09/2007
9	Transcatheter Aortic Valve Replacement 01/2020 - 09/2014
4	Ligation 01/2016 - 10/2006
3	Stents 01/2013 - 11/2009
2	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 05/2017 - 01/2017
1	Percutaneous Coronary Intervention 01/2021
1	Limb Salvage 06/2010
1	Thrombectomy 06/2010
1	Catheters 06/2010